GC L-Arginine

Overview
GC L-Arginine Injection is designed for medical use, particularly in managing acute hyperammonemia and serving as a diagnostic aid in growth hormone secretion testing. Formulated with L-Arginine Hydrochloride, this injection provides effective treatment when oral administration is insufficient or precise medical intervention is needed.

Indications and Effects

• Reduces blood ammonia levels in cases of:
  • Congenital urea cycle disorders such as Carbamyl phosphate synthetase deficiency, Ornithine transcarbamylase deficiency
  • Arginosuccinate synthetase deficiency, Arginosuccinate lyase deficiency, and lysinuric protein intolerance
• Functions as an acidifying agent for severe metabolic alkalosis
• Assists in pituitary function tests to measure growth hormone secretion, as an alternative or complement to insulin-induced hypoglycemia tests

Uses and Dosage

• Hyperammonemia Management: Administer 0.2–1g of L-Arginine hydrochloride per kg of body weight intravenously over 1 hour for acute control.
• Acidifying Agent: Dosage is based on plasma bicarbonate concentration and body weight.
• Growth Hormone Testing: Administer 500 mg of L-Arginine hydrochloride per kg as a 10% solution intravenously over 30 minutes.

Diagnostic Procedure

• Perform the test in the morning after fasting, with the patient resting for at least 30 minutes.
• Blood samples are collected at 0, 30, 60, 90, 120, and 150 minutes to monitor growth hormone secretion accurately.

Ingredients

• L-Arginine Hydrochloride: 0.6g/mL

Packaging

• Supplied in 25 mL vials, with 10 vials per package.

Important Note
This injection must be administered by healthcare professionals in a controlled environment, especially when managing complex metabolic disorders or conducting growth hormone diagnostics