Belissima is a next-generation collagen stimulator formulated with Poly-L-Lactic Acid (PLLA)—a biocompatible, biodegradable polymer trusted in medical use for over two decades. Specifically developed to address age-related volume loss and skin laxity, Belissima naturally activates the body’s collagen production, restoring youthful volume while reducing the appearance of fine lines and wrinkles.

Key Advantages

• Long-Lasting Results: Encourages natural collagen production to maintain volume for more than two years.

• Clinically Validated: FDA and Korean MFDS approved, using medically certified PLLA.

• Gradual, Natural Enhancement: Results appear progressively, improving skin texture and elasticity over time.

• Safe & Reliable: Proven low risk of adverse reactions; endorsed by Korean medical professionals.

• Efficient Treatment: Quick injection with minimal recovery and cost-effective preparation (mix with WFI + Lidocaine).

Mechanism of Action

Injected into the subcutaneous layer, Belissima initiates the wrinkle-smoothing process. As PLLA microspheres absorb water, they stimulate fibroblasts to produce collagen. Over time, new collagen forms around the microspheres, firming and lifting the skin. Eventually, the PLLA is absorbed, leaving behind a strengthened skin structure through enhanced collagen.

Scientific Superiority

Clinical studies show that the PLLA microspheres in Belissima outperform other forms in regenerating type I and III collagen. Histological analyses demonstrate clear improvements in dermal elasticity, texture, and volume at treated areas.

Why Belissima?

For Practitioners
✔ Clinically safe and CE-marked
✔ Easy to administer
✔ Economical and efficient

For Patients
✔ Natural-looking, subtle results
✔ Long-term aesthetic improvement
✔ Fast recovery
✔ Noticeable contour and wrinkle correction

Product Details

• Volume: 365mg per 5ml vial

• Indications:

  • Severe facial wrinkles and folds

  • Volume loss due to facial lipoatrophy

  • Facial contour irregularities

Belissima offers an elegant, scientifically backed solution for individuals seeking natural-looking facial rejuvenation with proven safety and lasting benefits.